Study finds target for potential cancer drugs may, worsen disease

Nov 15, 2021

New Delhi, Nov 15 (ANI): A recent study found a previously unrealized complexity in cancer development, one that raises concerns and caution about targeting Shp2 in oncological treatments. The findings were published in the journal Cell Reports. Shp2 is a phosphotyrosine phosphatase and its job is to remove phosphates from protein tyrosine residues. But Shp2 has also been shown to promote the growth and survival of many types of cancers. Many cancer patients respond well to primary treatment, which often gives patients and doctors an initial sense of excitement or hope. The findings challenge a currently popular approach in precision medicine.