Fri, May 01, 2026 | Updated 03:34 IST
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Mar 06, 2022
New Delhi, Mar 06 (ANI): A recent research has suggested that doing less exercise could deactivate a vital protein in the body, causing further inactivity and making exercise even more difficult. The paper on this, titled, 'Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity', was published in 'Journal of Clinical Investigation'. The study was funded by the British Heart Foundation. University of Leeds scientists discovered that deactivating the Piezo1 protein, a blood flow sensor, reduces the density of capillaries carrying blood to the muscles. This restricted blood flow meant that activity becomes more difficult and can lead to a reduction in how much exercise is possible, the team found. They said that the results helped in explaining the biology of why exercise becomes harder the less one does it.
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